Description
Product Characteristics:
Aliases: F13B antibody, Coagulation factor XIII B chain antibody, Fibrin-stabilizing factor B subunit antibody, Protein-glutamine gamma-glutamyltransferase B chain antibody, Transglutaminase B chain antibody
Target Information: This gene encodes subunit B of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit A to form a heterotetrameric protein that circulates in the plasma. During the blood coagulation process, thrombin-mediated proteolytic cleavage of the subunit A results in the dissociation of the encoded protein from the heterotetramer. Male mice lacking the encoded protein exhibit mild fibrosis together with hemosiderin deposits in the heart. [provided by RefSeq, Sep 2015]